The US-born giant panda Bei Bei has left his home at Washington's National Zoo for China.
Bei Bei will travel on a specially equipped flight from Washington to Chengdu, accompanied by his keeper and a veterinarian.
The giant panda turned four years - the age when all pandas born outside return to China under their breeding agreements.
"Today is bittersweet. We've cared for Bei Bei, and along with millions, watched him grow into a true ambassador for his species," said zoo director Steve Monfort.
"We look forward to continuing our 47-year giant panda conservation program and collaboration with Chinese colleagues to study, care for and help save the giant panda and its native habitat."
Zoo officials said they had prepared a special stash of treats for him: 30 kilos of bamboo, two pounds of apples and pears, two pounds of cooked sweet potatoes, two bags of biscuits and water.


US proposes plan to end Iran war, as Trump signals progress
US expected to send thousands more soldiers to Middle East
US safety agency says tracking system failed at LaGuardia during jet collision
Russia fires record 948 drones against Ukraine over 24 hours, Kyiv says
Death toll rises to 69 in Colombian military plane crash
One killed, five injured in Bahrain from Iran strikes
Qatar is not directly mediating between US and Iran, ministry spokesperson says
Germany, France in rare rebuke of Trump over Iran war
