Israeli forces are carrying out a "precise and targeted" military operation against Hamas "in a specific area" inside the Al Shifa Medical Complex in Gaza City.
The army said in a statement the operation is "based on intelligence information and operational necessities".
The IDF forces "include medical teams and Arabic speakers who have undergone specific training to prepare for this complex and sensitive environment, with the aim of not causing any harm to civilians who are used by Hamas as human shields".
The statement came shortly after the spokesman for the Hamas Ministry of Health in Gaza announced that Israel had informed officials that it would raid the Al-Shifa Hospital complex in the coming minutes.
On Tuesday, the US accused Hamas of running a "command and control center based from Al-Shifa Hospital."
Hamas has, however, denied militarising hospitals.
Medical officials in Gaza say more than 11,000 people are confirmed dead from Israeli strikes, around 40 per cent of them children, and countless others were trapped under rubble.
Iran rejects Trump's talk of negotiation as Israel and Iran launch airstrikes
Cyprus has opened discussion with UK over its bases, president says
Netanyahu seeks to avoid snap vote as Iran war gives no boost in polls
Luxury Paris hotel near Elysee reopens after fire forces brief closure
Germany renews push for sugar tax and energy drinks ban for children
No injuries reported as drone attack hits fuel tank at Kuwait's airport
US expected to send thousands more soldiers to Middle East
Philippines works with Washington to obtain oil from US-sanctioned countries
