Defending champions Manchester City remain 22 points behind Premier League leaders Liverpool.
Pep Guardiola's men missed a penalty and had a player sent off in a 2-0 defeat to Tottenham.
Both the goals came after City defender Oleksandr Zinchenko was sent off in the 60th minute for a second bookable offence.
Newly signed Dutch winger Steven Bergwijn (63') scored on his debut, while Son Heung-min doubled the lead just eight minutes later.
Spurs have moved up to fifth in the table, four points behind fourth-placed Chelsea.
Elsewhere, Arsenal have now drawn their last four top-flight games after their match with Burnley finished goalless.


Mumbai Indians promote Pollard to head coach, replacing Jayawardene
Leclerc laps fastest for Ferrari in first US GP practice
Bayern coach Kompany hospitalised after collapsing during training session
Alexander Volkanovski's title defence headlines UFC 333 in Abu Dhabi
Juventus fight back to draw with Rennes as Leverkusen go top
