Cristiano Ronaldo struck a late winner as his side came from a goal down to beat Scotland 2-1 and continue their strong start to the Nations League on Sunday.
After Bruno Fernandes had fired in Portugal's equaliser, Ronaldo pounced in the 88th minute for his 901st career goal.
Scotland were given hope of a first win against Portugal since 1980 as they took a shock lead through Scott McTominay's bullet header in the seventh minute.
But the visitors ended up with nothing to show for their efforts as 39-year-old Ronaldo again delivered for his country.
"The influence is always the same, regardless of whether he starts on the bench or not," Fernandes, who played his 600th career game, said of his former Manchester United team mate.
"Everyone who came on made the difference. Cristiano has a goal, today he scored 901 and now he's on his way to a thousand, which is what he wants."
Portugal lead League A Group 1 with six points after they started with a victory over Croatia, who are second on three following a 1-0 win against Poland on Sunday. Scotland have suffered two defeats, both of them to late goals.
Cristiano Ronaldo became the first player to score in six World Cups and Portugal’s all-time leading marksman at the global finals with two goals in Tuesday’s emphatic 5-0 Group K win over Uzbekistan in Houston.
The United States eased restrictions on the Iran squad's travel arrangements at the World Cup on Tuesday, allowing them to travel two days before their next match, the US Department of Homeland Security said.
Former Lucknow Super Giants captain Rishabh Pant will return to the Delhi Capitals while spinner Kuldeep Yadav will move the other way in a high-profile player trade in the Indian Premier League (IPL), the organisers said on Tuesday.
Algeria stormed back to beat Jordan 2-1 and eliminate the World Cup debutants with a match to spare on Monday thanks to second-half goals from substitute Nadhir Benbouali and Amine Gouiri.
Kylian Mbappe has scored his second double of the tournament as France eased into the last 32 with a 3-0 victory over Iraq on Monday in the first match of this World Cup beset by a lengthy weather stoppage.
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