Chelsea and Napoli have moved a step closer towards the quarter-finals of the UEFA Europa League, while Arsenal face an uphill task in reaching the next round.
The Gunners suffered a 3-1 defeat away to French side Rennes in the first leg of their last-16 match, while Chelsea outclassed Dynamo Kiev 3-0 and Napoli beat Red Bull Salzburg 3-0.
In other games, Villarreal were 3-1 winners away at Zenit St Petersburg, Sevilla were held 2-2 by Slavia Prague and Valencia overcame Krasnodar 2-1.
Elsewhere, Dinamo Zagreb registered a 1-0 home win over Benfica, while in the clash of former champions, Eintracht Frankfurt and Inter Milan played out a goalless draw.
Mumbai Indians promote Pollard to head coach, replacing Jayawardene
Leclerc laps fastest for Ferrari in first US GP practice
Bayern coach Kompany hospitalised after collapsing during training session
Alexander Volkanovski's title defence headlines UFC 333 in Abu Dhabi
Juventus fight back to draw with Rennes as Leverkusen go top
