Chelsea and Napoli have moved a step closer towards the quarter-finals of the UEFA Europa League, while Arsenal face an uphill task in reaching the next round.
The Gunners suffered a 3-1 defeat away to French side Rennes in the first leg of their last-16 match, while Chelsea outclassed Dynamo Kiev 3-0 and Napoli beat Red Bull Salzburg 3-0.
In other games, Villarreal were 3-1 winners away at Zenit St Petersburg, Sevilla were held 2-2 by Slavia Prague and Valencia overcame Krasnodar 2-1.
Elsewhere, Dinamo Zagreb registered a 1-0 home win over Benfica, while in the clash of former champions, Eintracht Frankfurt and Inter Milan played out a goalless draw.

Dubai World Cup: Godolphin-bred 'Banishing' wins Godolphin Mile
Ashwin becomes first India international to join US Major League
Mercedes driver Antonelli storms to second consecutive pole in Japan
Tiger Woods out on bail after arrest on suspicion of DUI
Iranian players hold schoolbags in protest over slain girls
