Unidentified armed men killed six people at a checkpoint 70 km east of Mali's capital Bamako, the security ministry said on Friday.
It did not say who was responsible for the attack, which took place overnight on Thursday in an area in southwestern Mali that has been relatively untouched by extremist insurgency ravaging central and northern regions.
Three of the people killed were members of the security forces, and three were civilians, the ministry said in an online post, without giving further details.
Mali is struggling to stem the insurgency that took root after a 2012 coup and has since spread from the West African country's arid north into neighbouring countries. As a result, thousands have died, and millions have been displaced across the Sahel region.
Some of the groups have links to al Qaeda and IS.


Blast at Damascus cafe kills nine, wounds 20
Rebels in Indonesia's Papua kill American pilot, burn plane
Russian air strikes kill 10, injure more than 50 in Ukraine's Kyiv
Firefighters battle wildfire in southern France
US, Iran talks conclude in Doha, focused on Strait of Hormuz
Trump honours Theodore Roosevelt in North Dakota, debuts new Air Force One
Kenyan court charges 8 schoolgirls with fellow students' murder
At least 5 people killed in fire in Antwerp apartment block
