German prosecutors believe British girl Madeleine McCann, who disappeared in Portugal in 2007, is dead.
"We assume that the girl is dead," Braunschweig state prosecutor Hans Christian Wolters said on Thursday.
It comes after an imprisoned German child abuser has been identified as a murder suspect.
While his name has not been revealed, the Metropolitan Police said he is 43-years-old and had been in and around the Praia da Luz resort in Algarve at the time of her disappearance.
"All we have ever wanted is to find her, uncover the truth and bring those responsible to justice," her parents, Kate and Gerry, said in a statement issued before the German prosecutor spoke.
"We will never give up hope of finding Madeleine alive but whatever the outcome may be, we need to know as we need to find peace."
McCann's disappearance from her room on May 3 during a family vacation in Algarve while her parents were dining with friends nearby had sparked an international search.
An Israeli air strike has killed at least three people in the Gaza Strip on Monday, local health officials said, in the latest round of violence since a US-brokered ceasefire took effect more than five months ago.
Spain has closed its airspace to US planes involved in attacks on Iran, a step beyond its previous denial of use of jointly-operated military bases, Spanish newspaper El Pais reported on Monday, citing military sources.
A United Nations peacekeeper has been killed in southern Lebanon overnight, prompting condemnations on Monday after a weekend in which Lebanese journalists and medics were killed in Israeli strikes.
Kuwait's Ministry of Electricity, Water, and Renewable Energy has announced on Sunday that an Iranian attack has killed one worker and damaged a service building at one of its power and water distillation plants.
Iran said it was ready to respond to a US ground attack, accusing Washington on Sunday of preparing a land assault even as the Trump administration sought talks and as regional powers met in Pakistan to try to end the conflict.
Heavy rain that triggered severe flooding and caused buildings to collapse has killed 22 people and injured 32 in Afghanistan over the last two days, the country's National Disaster Management Authority (NDMA) said on Monday, as it warned of continued risk due to bad weather.
Australian police have shot dead a fugitive gunman who had been on the run since August after allegedly killing two officers in the state of Victoria, Australian media reported on Monday.
Israeli Prime Minister Benjamin Netanyahu said on Sunday he had instructed the military to further expand the existing security buffer zone in southern Lebanon, vowing to fundamentally change the security situation there.
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