Iran's consulate in the Syrian capital Damascus was flattened on Monday in what Syrian and Iranian media described as an Israeli air strike.
A Lebanese security source, speaking to Reuters, said one of the dead was Mohammad Reza Zahedi, a senior commander in Iran's Revolutionary Guards Corps (IRGC). Iranian state television said several Iranian diplomats had been killed.
Israel, which has repeatedly hit Iranian targets during the six-month war in Gaza, declined to comment on the incident, following its usual practice.
An Israeli military spokesperson said: "We do not comment on reports in the foreign media."
Iran's Tasnim news agency said five people were killed in the Israeli strike. Syria's SANA state news agency reported an unspecified number of deaths and injuries.
Since the Palestinian group Hamas' attack on Israel on October 7, Israel has ramped up airstrikes in Syria against Lebanon's Hezbollah militia and Iran's Guards, both of which support the government of President Bashar Al Assad.
Qatar's Ministry of Defence has announced that an oil tanker was struck by a cruise missile in its territorial waters on Wednesday, with no casualties reported.
Australian Prime Minister Anthony Albanese has warned the economic shocks of the war in the Middle East would be felt for months and encouraged citizens to take public transport in a rare address to the nation on Wednesday.
An Iranian drone attack has targeted fuel tanks at Kuwait International Airport on Wednesday, causing a major fire that broke out at the site, with no injuries reported.
At least 18 people were killed when an inflatable boat carrying migrants sank off Turkey's western province of Mugla on Wednesday, the coastguard said in a statement, adding that search and rescue efforts continued in the area.
US Secretary of State Marco Rubio has said on Tuesday that Washington could see the "finish line" in the Iran war, which is now in its fifth week, and the US will have to reexamine ties with NATO after the conflict.
Bahrain's Interior Ministry has announced on Wednesday that its civil defence teams were extinguishing a fire at a company facility caused by an Iranian attack.
US Defence Secretary Pete Hegseth said on Tuesday the next few days in the war against Iran would be decisive and warned Tehran the conflict would intensify if it did not make a deal, while Iran said it will target US companies in the region from Wednesday.
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