US Secretary of State Antony Blinken will focus on stepping up efforts to protect the lives of Palestinian civilians in Gaza during his talks with Israeli Prime Minister Benjamin Netanyahu in Tel Aviv on Friday.
Blinken, who is on his second trip to Israel in a month, will also hold talks with senior Israeli leaders.
Before leaving for Tel Aviv, the US diplomat said he would discuss taking concrete steps to minimise harm to civilians in Gaza, where food, fuel, water and medicine are running out.
The White House said any pauses in fighting should be temporary and localised, and reiterated it would not prevent Israel from defending itself.
Calls from world leaders for a truce or ceasefire have increased in light of the increasing number of deaths among Palestinian civilians.
Gaza health authorities say that at least 9,061 people have been killed in Gaza since Israel launched its attack on the Strip, in response to a Hamas attack on southern Israel.
Israel says Hamas killed 1,400 people, mostly civilians, and took more than 240 hostages in the attacks on October 7.


Damascus cafe blast kills 5, wounds 16
Rebels in Indonesia's Papua kill American pilot, burn plane
Russian air strikes kill 10, injure more than 50 in Ukraine's Kyiv
Firefighters battle wildfire in southern France
US, Iran talks conclude in Doha, focused on Strait of Hormuz
Trump honours Theodore Roosevelt in North Dakota, debuts new Air Force One
Kenyan court charges 8 schoolgirls with fellow students' murder
At least 5 people killed in fire in Antwerp apartment block
