Bahrain will suspend dine-in services at restaurants and cafes and move public and private schools to remote learning for three weeks to contain the spread of the coronavirus, the health ministry said.
It said it had detected a new variant of coronavirus in a number of cases, without specifying which kind.
The new lockdown measures will come into effect on Sunday.
There has been an uptick in coronavirus cases in the Gulf kingdom since December. The country registered 459 new cases on Wednesday, adding to a total of nearly 100,000 since the start of the pandemic, with 370 deaths.
The small island state has the third highest rate of vaccinations per capita in the world so far, according to the Our World in Data website, which is run by an Oxford University research programme.
Bahrain offers its citizens either the Pfizer/BioNTech vaccine or one manufactured by Chinese state-backed pharmaceutical giant Sinopharm free of charge.
The kingdom also approved the AstraZeneca COVID-19 vaccine on Monday for emergency use.
Iran denied on Monday that it had engaged in negotiations with the United States, after President Donald Trump postponed a threat to bomb Iran's power grid because of what he described as productive talks with unidentified Iranian officials.
President Volodymyr Zelenskiy said on Monday that Ukrainian intelligence believed Russian forces were preparing a new, imminent mass attack on the country.
At least seven rockets were launched from the Iraqi town of Rabi'a towards a US military base in northeastern Syria on Monday, two Iraqi security sources said, the first attack of its kind since the start of the US-Israeli military campaign on Iran.
At least one person was killed and 77 others hospitalised when a Colombian Air Force plane carrying 125 people crashed just after takeoff deep in the country's southern Amazon region on Monday.
Hong Kong police can now demand that people suspected of breaching the city's national security law provide mobile phone or computer passwords in a further crackdown on dissent.
US immigration agents began deploying at more than a dozen US airports on Monday to aid security screening as staffing absences by unpaid airport security officers have caused massive delays.
An Air Canada Express jet collided with a fire truck while landing at New York's LaGuardia airport late on Sunday, killing both pilots, injuring dozens and closing the facility, authorities said.
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