Serena Williams has missed out on winning a record-equalling 24th Grand Slam singles title on home soil this year.
She was beaten 1-6, 6-3, 6-3 in the semi-finals of the U.S. Open by Victoria Azarenka.
The unseeded Belarusian will play Japan's Naomi Osaka in the final on Saturday.
It will be Azarenka's third final at Flushing Meadows, having lost the previous two to Williams in 2012 and 2013.
Fourth seed Osaka had earlier beaten 28th seed Jennifer Brady 7-6, 3-6, 6-3 in the other semi-final.
Zverev brushes aside Darderi to reach US Open quarter-finals
Alexander Zverev has put a slow start to his US Open campaign further behind him as the top-seeded German defeated Italian Luciano Darderi 6-2 6-2 7-6(3) on Monday and moved into the quarter-finals.
Gauff downs fellow American Jovic to reach US Open last eight
Fourth seed Coco Gauff has stayed on course for a third Grand Slam title after reaching the US Open quarter-finals with a 6-1 6-4 win over fellow American Iva Jovic at Arthur Ashe Stadium on Monday.
Liam Lawson to replace injured Isack Hadjar again in Madrid
Liam Lawson will race alongside Red Bull superstar Max Verstappen for this weekend's Spanish Grand Prix with Isack Hadjar still sidelined by a wrist injury.
Rybakina thumps Osaka to reach US Open quarters, close in on top ranking
Elena Rybakina has cleared another big hurdle in her bid to win a third Grand Slam title by outclassing former US Open champion Naomi Osaka 6-1 6-4 on Monday to reach the quarter-finals at Flushing Meadows.
Zheng stuns Swiatek at US Open as Andreeva extends winning run
Chinese qualifier Zheng Qinwen produced another spectacular fight back to upset six-times major winner Iga Swiatek 7-5 6-3 in the US Open on Monday, recovering from 0-5 down in the opening set to reach the quarter-finals.
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Pinoy Expat Corner
Why did they choose mountain biking as their sport? What makes mountain biking different from regular road cycling?
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Pinoy Expat Corner
Why is it important for them to preserve Ilokano culture and traditions even while living far from the Philippines?
