Hundreds of protesters battled police in the heart of Barcelona amid anger over the jailing of Catalan separatist leaders.
Masked protestors were seen blocking areas, damaging police vehicles, setting fire to large garbage bins, ransacking banks and attacking riot police officers with stones, cans and bottles.
Police responded with repeated volleys of foam bullets, smoke grenades, tear gas and water cannons.
The violence followed a largely peaceful demonstration that drew more than half a million people onto the streets of the Catalan capital.
Catalan interior affairs chief Miquel Buch distanced themselves from the riots, claiming "this kind of violence is unprecedented in Catalonia ... these people are not separatists".
Some 128 people have been arrested in the region over the past five days, with Spain's acting interior minister, Fernando Grande-Marlaska, warning that rioters faced up to six years in prison.
China's Xi Jinping told US President Donald Trump that trade talks were making progress at the start of a two-day summit on Thursday but warned that disagreement over Taiwan could send relations down a dangerous path.
Ukraine's anti-corruption court on Thursday ordered the arrest of Andriy Yermak, a close ally of President Volodymyr Zelenskyy and former head of his administration, on money-laundering charges.
The Philippine Senate will convene as an impeachment court on May 18 ahead of the trial of Vice President Sara Duterte, its president said on Thursday, with tensions flaring as the country's most powerful political clans face off.
Almost 90 people were killed in a violent storm that pounded India's most populous state of Uttar Pradesh with rain and hail, a state official said on Thursday.
Russia pummeled the Ukrainian capital Kyiv and several other regions in a massive aerial attack, officials said on Thursday, killing at least one person and wounding dozens.
Interior ministers of the Gulf Cooperation Council (GCC) have held an emergency ministerial meeting in Riyadh, chaired by the Kingdom of Bahrain, according to the Saudi Press Agency.
Gunshots broke out in chaotic scenes at the Philippine Senate on Wednesday where troops had been deployed after a politician wanted by the International Criminal Court urged supporters to mobilise and thwart his imminent arrest.
US President Donald Trump and an entourage that included Nvidia's Jensen Huang and Elon Musk were greeted with a lavish welcome in Beijing on Wednesday as he prepared to ask China's Xi Jinping to "open up" to US business at the start of their two-day summit.
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